Inhibitory Effect of (—)‐Epigallocatechin Gallate on Carcinogenesis with N‐Ethyl‐N′‐nitro‐N‐nitrosoguanidine in Mouse Duodenum

(—)‐Epigallocatechin gallate (EGCG) is the main polyphenolic constituent of green tea infusion and inhibits tumor promotion by teleocidin in two‐stage carcinogenesis on mouse skin. In this work, EGCG was found to inhibit tumor promotion in the gastrointestinal tract in a model system of mouse duoden...

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Detalles Bibliográficos
Autores principales: Fujita, Yoshihiro, Yamane, Tetsuro, Tanaka, Masumi, Kuwata, Katsuya, Okuzumi, Junichi, Takahashi, Toshio, Fujiki, Hirota, Okuda, Takuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917795/
https://www.ncbi.nlm.nih.gov/pubmed/2503469
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01666.x
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author Fujita, Yoshihiro
Yamane, Tetsuro
Tanaka, Masumi
Kuwata, Katsuya
Okuzumi, Junichi
Takahashi, Toshio
Fujiki, Hirota
Okuda, Takuo
author_facet Fujita, Yoshihiro
Yamane, Tetsuro
Tanaka, Masumi
Kuwata, Katsuya
Okuzumi, Junichi
Takahashi, Toshio
Fujiki, Hirota
Okuda, Takuo
author_sort Fujita, Yoshihiro
collection PubMed
description (—)‐Epigallocatechin gallate (EGCG) is the main polyphenolic constituent of green tea infusion and inhibits tumor promotion by teleocidin in two‐stage carcinogenesis on mouse skin. In this work, EGCG was found to inhibit tumor promotion in the gastrointestinal tract in a model system of mouse duodenal carcinogenesis with N‐ethyl‐N′‐nitro‐N‐nitrosoguanidine. The duodenal tumors that developed were studied stereomicroscopically and histologically.
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spelling pubmed-59177952018-05-11 Inhibitory Effect of (—)‐Epigallocatechin Gallate on Carcinogenesis with N‐Ethyl‐N′‐nitro‐N‐nitrosoguanidine in Mouse Duodenum Fujita, Yoshihiro Yamane, Tetsuro Tanaka, Masumi Kuwata, Katsuya Okuzumi, Junichi Takahashi, Toshio Fujiki, Hirota Okuda, Takuo Jpn J Cancer Res Rapid Communication (—)‐Epigallocatechin gallate (EGCG) is the main polyphenolic constituent of green tea infusion and inhibits tumor promotion by teleocidin in two‐stage carcinogenesis on mouse skin. In this work, EGCG was found to inhibit tumor promotion in the gastrointestinal tract in a model system of mouse duodenal carcinogenesis with N‐ethyl‐N′‐nitro‐N‐nitrosoguanidine. The duodenal tumors that developed were studied stereomicroscopically and histologically. Blackwell Publishing Ltd 1989-06 /pmc/articles/PMC5917795/ /pubmed/2503469 http://dx.doi.org/10.1111/j.1349-7006.1989.tb01666.x Text en
spellingShingle Rapid Communication
Fujita, Yoshihiro
Yamane, Tetsuro
Tanaka, Masumi
Kuwata, Katsuya
Okuzumi, Junichi
Takahashi, Toshio
Fujiki, Hirota
Okuda, Takuo
Inhibitory Effect of (—)‐Epigallocatechin Gallate on Carcinogenesis with N‐Ethyl‐N′‐nitro‐N‐nitrosoguanidine in Mouse Duodenum
title Inhibitory Effect of (—)‐Epigallocatechin Gallate on Carcinogenesis with N‐Ethyl‐N′‐nitro‐N‐nitrosoguanidine in Mouse Duodenum
title_full Inhibitory Effect of (—)‐Epigallocatechin Gallate on Carcinogenesis with N‐Ethyl‐N′‐nitro‐N‐nitrosoguanidine in Mouse Duodenum
title_fullStr Inhibitory Effect of (—)‐Epigallocatechin Gallate on Carcinogenesis with N‐Ethyl‐N′‐nitro‐N‐nitrosoguanidine in Mouse Duodenum
title_full_unstemmed Inhibitory Effect of (—)‐Epigallocatechin Gallate on Carcinogenesis with N‐Ethyl‐N′‐nitro‐N‐nitrosoguanidine in Mouse Duodenum
title_short Inhibitory Effect of (—)‐Epigallocatechin Gallate on Carcinogenesis with N‐Ethyl‐N′‐nitro‐N‐nitrosoguanidine in Mouse Duodenum
title_sort inhibitory effect of (—)‐epigallocatechin gallate on carcinogenesis with n‐ethyl‐n′‐nitro‐n‐nitrosoguanidine in mouse duodenum
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917795/
https://www.ncbi.nlm.nih.gov/pubmed/2503469
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01666.x
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