Cargando…

Dose‐Response Carcinogenicity in Rats on Low‐dose Levels of N‐Ethyl‐N‐nitrosourethane

A dose‐response study on the carcinogenicity of N‐ethyl‐N‐nitrosourethane (ENUR) was undertaken to examine its effect at low doses. Six‐week‐old female F344 rats were divided into 5 groups, each consisting of 40 animals. ENUR was dissolved in distilled water at dose levels of 0 (control), 0.15, 0.6,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maekawa, Akihiko, Onodera, Hiroshi, Matsushima, Yuko, Nagaoka, Takaharu, Todate, Asahi, Shibutani, Makoto, Kodama, Yukio, Hayashi, Yuzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1989
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917814/ https://www.ncbi.nlm.nih.gov/pubmed/2507486 http://dx.doi.org/10.1111/j.1349-7006.1989.tb01689.x

Ejemplares similares

High Yields of Granulosa Cell Tumors/Luteomas in F344 Rat Ovaries after Transplacental Administration of N‐Nitrosobis(2‐oxopropyl)amine
por: Maekawa, Akihiko, et al.
Publicado: (1990)

Tumours of the intestines induced in rats by intraperitoneal injections of N-methyl- and N-ethyl-N-nitrosourethanes.
por: Schoental, R., et al.
Publicado: (1968)

Enhancement by bracken of induction of tumours of the upper alimentary tract by N-propyl-N-nitrosourethan.
por: Hirono, I., et al.
Publicado: (1982)

Uterine Adenocarcinoma in N‐Ethyl‐N‐nitro‐N‐nitrosoguanidine‐treated Rats with High‐dose Exposure to p‐tert‐Octylphenol during Adulthood
por: Katsuda, Shin‐ichi, et al.
Publicado: (2002)

The multipotential carcinogenic action of N-ethyl-N-nitrosourea administered neonatally to mice.
por: Searle, C. E., et al.
Publicado: (1976)

Proceedings: Strain differences in the carcinogenic action of N-ethyl-N-nitrosourea (ENU) in mice.
por: Searle, C. E., et al.
Publicado: (1974)

High Susceptibility of Analbuminemic Rats to Neurogenic Tumor Induction by Transplacental Administration of N‐Ethyl‐N‐nitrosourea
por: Usuki, Seigou, et al.
Publicado: (1992)

Synthesis and secretion of albumin in rats during treatment with a carcinogenic dose of N-2-acetylaminofluorene.
por: Harson, M. M., et al.
Publicado: (1979)

Toxicity and carcinogenicity of potassium bromate--a new renal carcinogen.
por: Kurokawa, Y, et al.
Publicado: (1990)

Genomic analysis of microRNA time-course expression in liver of mice treated with genotoxic carcinogen N-ethyl-N-nitrosourea
por: Li, Zhiguang, et al.
Publicado: (2010)

Effects of Reproduction on Spontaneous Development of Endometrial Adenocarcinomas and Mammary Tumors in Donryu Rats
por: Nagaoka, Takaharu, et al.
Publicado: (2000)

Nonlinearity of dose-response functions for carcinogenicity.
por: Hoel, D G, et al.
Publicado: (1994)

Dose-response relationships for carcinogens: a review.
por: Zeise, L, et al.
Publicado: (1987)

Dose response in the tetrazolium test for skin carcinogenicity.
por: Iversen, O. H.
Publicado: (1980)

High‐yield Induction of Uterine Endometrial Adenocarcinomas in Donryu Rats by a Single Intra‐uterine Administration of N‐Ethyl‐N‐nitro‐N‐nitrosoguanidine via the Vagina
por: Ando‐Lu, Jin, et al.
Publicado: (1994)

Lack of a Dose‐response Relationship for Carcinogenicity in the Rat Liver with Low Doses of 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline or N‐Nitrosodiethylamine
por: Fukushima, Shoji, et al.
Publicado: (2002)

The Carcinogenic Activity of N-Monomethyl- and N-Dimethyl-2-aminofluorene
por: Bielschowsky, F., et al.
Publicado: (1952)

High- to low-dose extrapolation: critical determinants involved in the dose response of carcinogenic substances.
por: Swenberg, J A, et al.
Publicado: (1987)

Best-estimate low-dose extrapolation of carcinogenicity data.
por: Guess, H A, et al.
Publicado: (1978)

Pulmonary carcinogenicity of inhaled particles and the maximum tolerated dose.
por: Oberdörster, G
Publicado: (1997)

N-Ethyl-N-phenyl-N′-tosylformamidine
por: Shen, Heng-Shui, et al.
Publicado: (2009)

Experimental induction of ovarian Sertoli cell tumors in rats by N-nitrosoureas.
por: Maekawa, A, et al.
Publicado: (1987)

N-Benzyl-N-ethylmorpholinium chloride
por: Bian, Yan-Jiang
Publicado: (2008)

Inhibition of N-2-fluorenyldiacetamide induced hepatic carcinogenesis in rats by chloramphenicol: a dose-related phenomenon with reduced protein binding of carcinogen.
por: Oster, W. F., et al.
Publicado: (1971)

tert-Butyl N-[N,N-bis(2-chloroethyl)sulfamoyl]-N-(2-chloroethyl)carbamate
por: Seridi, Achour, et al.
Publicado: (2009)

Methyl ethyl ketone and methyl isobutyl ketone not carcinogenic.
por: Strickland, G D
Publicado: (1993)

N-hydroxylation of carcinogenic and mutagenic aromatic amines.
por: Kato, R, et al.
Publicado: (1983)

Dose-response analyses of the carcinogenic effects of trichloroethylene in experimental animals.
por: Rhomberg, L R
Publicado: (2000)

N,N,N′,N′-Tetraethylpyridine-2,6-dicarboxamide
por: Pojarová, Michaela, et al.
Publicado: (2011)

N,N,N′,N′-Tetrakis(2-hydroxyethyl)terephthalamide
por: Wang, Zhi-Qiang, et al.
Publicado: (2008)

Sublinear response in lacZ mutant frequency of Muta(™)Mouse spermatogonial stem cells after low dose subchronic exposure to N‐ethyl‐N‐nitrosourea
por: O'Brien, Jason M., et al.
Publicado: (2015)

Occupational Exposure Limits of lead, dimethylamine, n-butyl-2,3-epoxypropyl ether, and 2-ethyl-1-hexanol and carcinogenicity and occupational sensitizer classification
por: Azuma, Kenichi, et al.
Publicado: (2016)

N,N′-Dicyclohexylethylenediammonium dichloride
por: Lechner, Bob-Dan, et al.
Publicado: (2009)

N-Ethyl-N-phenyl-p-toluenesulfonamide
por: Khan, Islam Ullah, et al.
Publicado: (2010)

N,N-Bis(diphenylphosphino)ethylamine
por: Cloete, Nicoline, et al.
Publicado: (2009)

N-Cyclohexyl-N-ethylbenzenesulfonamide
por: Khan, Islam Ullah, et al.
Publicado: (2009)

N,N′-Di-p-tolylethylenediamine
por: Tian, Wen-Wen, et al.
Publicado: (2007)

N,N-Bis(2-bromoethyl)aniline
por: Bojan, R. Vilma, et al.
Publicado: (2007)

Renal Transcriptomics Reveals the Carcinogenic Mechanism of Ethyl Carbamate in Musalais
por: Wang, Weihua, et al.
Publicado: (2021)

Time‐ and Dose‐dependent Induction of Invasive Urinary Bladder Cancers by N‐Ethyl‐N‐(4‐hydroxybutyl)nitrosamine in B6C3F(1) Mice
por: Tamano, Seiko, et al.
Publicado: (1991)

Cannot write session to /tmp/vufind_sessions/sess_gg66ai05covg2nbck55kke5l0s