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Inhibition of Multidrug‐resistant Human Tumor Growth in Athymic Mice by Anti‐P‐glycoprotein Monoclonal Antibodies
In an effort to devise an effective treatment for human drug‐resistant cancers, we have developed monoclonal antibodies, MRK16 and 17, reactive to the multidrug transporter protein, P‐glycoprotein. The monoclonal antibodies given intravenously effectively prevented tumor development in athymic mice...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1989
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917818/ https://www.ncbi.nlm.nih.gov/pubmed/2571602 http://dx.doi.org/10.1111/j.1349-7006.1989.tb01688.x |