Induction of Squamous Metaplasia, Dysplasia and Carcinoma in situ of the Mouse Tracheal Mucosa by Inhalation of Sodium Chloride Mist Following Subcutaneous Injection of 4‐Nitroquinoline 1‐Oxide

Squamous metaplasia, dysplasia and carcinoma in situ (CIS) were induced in the ICR/Jcl mouse tracheal mucosa by exposure to a mist of 5% NaCl solution following single subcutaneous injection of 4‐nitroquinoline 1‐oxide (4‐NQO). Either subcutaneous injection of 4‐NQO or NaCl inhalation alone did not...

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Detalles Bibliográficos
Autores principales: Karube, Toshiaki, Katayama, Hiroo, Takemoto, Kazuo, Watanabe, Shaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917826/
https://www.ncbi.nlm.nih.gov/pubmed/2511173
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01699.x
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author Karube, Toshiaki
Katayama, Hiroo
Takemoto, Kazuo
Watanabe, Shaw
author_facet Karube, Toshiaki
Katayama, Hiroo
Takemoto, Kazuo
Watanabe, Shaw
author_sort Karube, Toshiaki
collection PubMed
description Squamous metaplasia, dysplasia and carcinoma in situ (CIS) were induced in the ICR/Jcl mouse tracheal mucosa by exposure to a mist of 5% NaCl solution following single subcutaneous injection of 4‐nitroquinoline 1‐oxide (4‐NQO). Either subcutaneous injection of 4‐NQO or NaCl inhalation alone did not cause any marked change in the tracheal mucosa. The NaCl inhalation is considered to have promotion‐like action on the mouse tracheal mucosa after administration of 4‐NQO injection.
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spelling pubmed-59178262018-05-11 Induction of Squamous Metaplasia, Dysplasia and Carcinoma in situ of the Mouse Tracheal Mucosa by Inhalation of Sodium Chloride Mist Following Subcutaneous Injection of 4‐Nitroquinoline 1‐Oxide Karube, Toshiaki Katayama, Hiroo Takemoto, Kazuo Watanabe, Shaw Jpn J Cancer Res Rapid Communication Squamous metaplasia, dysplasia and carcinoma in situ (CIS) were induced in the ICR/Jcl mouse tracheal mucosa by exposure to a mist of 5% NaCl solution following single subcutaneous injection of 4‐nitroquinoline 1‐oxide (4‐NQO). Either subcutaneous injection of 4‐NQO or NaCl inhalation alone did not cause any marked change in the tracheal mucosa. The NaCl inhalation is considered to have promotion‐like action on the mouse tracheal mucosa after administration of 4‐NQO injection. Blackwell Publishing Ltd 1989-08 /pmc/articles/PMC5917826/ /pubmed/2511173 http://dx.doi.org/10.1111/j.1349-7006.1989.tb01699.x Text en
spellingShingle Rapid Communication
Karube, Toshiaki
Katayama, Hiroo
Takemoto, Kazuo
Watanabe, Shaw
Induction of Squamous Metaplasia, Dysplasia and Carcinoma in situ of the Mouse Tracheal Mucosa by Inhalation of Sodium Chloride Mist Following Subcutaneous Injection of 4‐Nitroquinoline 1‐Oxide
title Induction of Squamous Metaplasia, Dysplasia and Carcinoma in situ of the Mouse Tracheal Mucosa by Inhalation of Sodium Chloride Mist Following Subcutaneous Injection of 4‐Nitroquinoline 1‐Oxide
title_full Induction of Squamous Metaplasia, Dysplasia and Carcinoma in situ of the Mouse Tracheal Mucosa by Inhalation of Sodium Chloride Mist Following Subcutaneous Injection of 4‐Nitroquinoline 1‐Oxide
title_fullStr Induction of Squamous Metaplasia, Dysplasia and Carcinoma in situ of the Mouse Tracheal Mucosa by Inhalation of Sodium Chloride Mist Following Subcutaneous Injection of 4‐Nitroquinoline 1‐Oxide
title_full_unstemmed Induction of Squamous Metaplasia, Dysplasia and Carcinoma in situ of the Mouse Tracheal Mucosa by Inhalation of Sodium Chloride Mist Following Subcutaneous Injection of 4‐Nitroquinoline 1‐Oxide
title_short Induction of Squamous Metaplasia, Dysplasia and Carcinoma in situ of the Mouse Tracheal Mucosa by Inhalation of Sodium Chloride Mist Following Subcutaneous Injection of 4‐Nitroquinoline 1‐Oxide
title_sort induction of squamous metaplasia, dysplasia and carcinoma in situ of the mouse tracheal mucosa by inhalation of sodium chloride mist following subcutaneous injection of 4‐nitroquinoline 1‐oxide
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917826/
https://www.ncbi.nlm.nih.gov/pubmed/2511173
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01699.x
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