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Inhibition of in vitro Tumor Cell Invasion by Transmethylation Inhibitors

Three inhibitors of S‐adenosylmethionine‐mediated transmethylation, 5′‐methylthioadenosine (MTA), 2′‐deoxyadenosine and sinefungin, inhibited in vitro invasion by a highly invasive clone (Cl‐30) of rat ascites hepatoma cells, AH 130 (AH cells). Difluoromethylthioadenosine (DFMTA), a non‐metabolizabl...

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Detalles Bibliográficos
Autores principales: Sbinkai, Kiyoko, Mukai, Mutsuko, Horai, Takeshi, Ohigashi, Hiroaki, Nishikawa, Seiji, Inoue, Hideo, Takeda, Yoshiro, Akedo, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917839/
https://www.ncbi.nlm.nih.gov/pubmed/2555319
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01703.x