Alternagin-C binding to α(2)β(1) integrin controls matrix metalloprotease-9 and matrix metalloprotease-2 in breast tumor cells and endothelial cells

BACKGROUND: Matrix metalloproteinases (MMPs) are key players in tumor progression, helping tumor cells to modify their microenvironment, which allows cell migration to secondary sites. The role of integrins, adhesion receptors that connect cells to the extracellular matrix, in MMP expression and act...

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Detalles Bibliográficos
Autores principales: Moritz, Milene Nóbrega de Oliveira, Eustáquio, Lívia Mara Santos, Micocci, Kelli Cristina, Nunes, Ana Carolina Caetano, dos Santos, Patty Karina, de Castro Vieira, Tamires, Selistre-de-Araujo, Heloísa Sobreiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917863/
https://www.ncbi.nlm.nih.gov/pubmed/29713337
http://dx.doi.org/10.1186/s40409-018-0150-2

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