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Multidrug Resistance in Cultured Human Leukemia and Lymphoma Cell Lines Detected by a Monoclonal Antibody, MRK16

Forty cultured human leukemia and lymphoma cell lines never exposed to anticancer agents in culture, apart from doxorubicin (ADM)‐resistant K562/ADM, were examined for reactivity with a monoclonal antibody, MRK16 in F(ab′)(2) form [MRK16‐F(ab′)(2)], which recognizes P‐glycoprotein (P‐gp). The relati...

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Detalles Bibliográficos
Autores principales: Ishida, Yasushi, Ohtsu, Tomoko, Hamada, Hirofumi, Sugimoto, Yoshikazu, Tobinai, Kensei, Minato, Keisuke, Tsuruo, Takashi, Shimoyama, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917883/
https://www.ncbi.nlm.nih.gov/pubmed/2575608
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01641.x