Mutagenicity Arising from Boiled Rice on Treatment with Nitrous Acid

When an aqueous homogenate of boiled rice was treated with nitrous acid at pH 3, direct‐acting mutagens were formed. The presence of the mutagens was demonstrated by isolating the mutagenic fractions through blue‐rayon adsorption, a method used to extract polycyclic compounds, and subsequent high‐pe...

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Detalles Bibliográficos
Autores principales: Hayatsu, Hikoya, Hayatsu, Toshiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917898/
https://www.ncbi.nlm.nih.gov/pubmed/2514162
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02252.x
Descripción
Sumario:When an aqueous homogenate of boiled rice was treated with nitrous acid at pH 3, direct‐acting mutagens were formed. The presence of the mutagens was demonstrated by isolating the mutagenic fractions through blue‐rayon adsorption, a method used to extract polycyclic compounds, and subsequent high‐performance liquid chromatography (HPLC). The mutagens were active in Salmonella typhimurium TA100 and TA98 without metabolic activation. Several different mutagens were formed, as judged from the HPLC profile.

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