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Detection of Multidrug Resistance (MDR1) Gene RNA Expression in Human Tumors by a Sensitive Ribonuclease Protection Assay

The human MDR1 gene encoding P‐glycoprotein, an energy‐dependent drug‐efflux pump, was initially isolated from a multidrug‐resistant KB carcinoma cell. When a 3 kb genomlc sequence isolated from normal human tissue including the major downstream promoter and the first and second exons of the MDR1 ge...

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Detalles Bibliográficos
Autores principales:	Ueda, Kazumitsu, Yamano, Yoshiaki, Kioka, Noriyuki, Kakehi, Yoshiyuki, Yoshida, Osamu, Gottesman, Michael M., Pastan, Ira, Komano, Tohru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1989
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917905/ https://www.ncbi.nlm.nih.gov/pubmed/2481665 http://dx.doi.org/10.1111/j.1349-7006.1989.tb02269.x

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