Contrasting Actions of Estradiol on the Growth of Human Gastric Cancer Xenografts in Nude Mice

The effects of estradiol on the growth of six human gastric xenografts in nude mice were studied and diverse effects were found, including one case of stimulation, two of inhibition and three of unchanged condition. Neither the histological features of the original tumor nor the estrogen‐binding cap...

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Detalles Bibliográficos
Autores principales: Tokunaga, Akira, Onda, Masahiko, Kiyama, Teruo, Nishi, Keigo, Mizutani, Takashi, Yoshiyuki, Toshiro, Shimizu, Yasuhito, Matsukura, Norio, Tanaka, Noritake, Asano, Goro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917919/
https://www.ncbi.nlm.nih.gov/pubmed/2516842
http://dx.doi.org/10.1111/j.1349-7006.1989.tb01646.x
Descripción
Sumario:The effects of estradiol on the growth of six human gastric xenografts in nude mice were studied and diverse effects were found, including one case of stimulation, two of inhibition and three of unchanged condition. Neither the histological features of the original tumor nor the estrogen‐binding capacity seemed to be related to the response to estradiol. It is concluded that the growth of human gastric cancer can be modulated by estradiol.

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