Transition of Antibody to Hepatitis C Virus from Chronic Hepatitis to Hepatocellular Carcinoma

Fifty‐eight patients with chronic hepatitis C were followed for more than 7 years. Of them, 10 patients were found to develop hepatocellular carcinoma, 14 to develop liver cirrhosis, 30 to sustain chronic hepatitis, and 4 to show subsidence of hepatitis. Antibody to hepatitis C virus (anti‐HCV) disa...

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Autores principales: Kiyosawa, Kendo, Tanaka, Eiji, Sodeyama, Takeshi, Furuta, Kiyoshi, Usuda, Seiichi, Yousuf, Muhammad, Furuta, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917992/
https://www.ncbi.nlm.nih.gov/pubmed/2176199
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02517.x
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author Kiyosawa, Kendo
Tanaka, Eiji
Sodeyama, Takeshi
Furuta, Kiyoshi
Usuda, Seiichi
Yousuf, Muhammad
Furuta, Seiichi
author_facet Kiyosawa, Kendo
Tanaka, Eiji
Sodeyama, Takeshi
Furuta, Kiyoshi
Usuda, Seiichi
Yousuf, Muhammad
Furuta, Seiichi
author_sort Kiyosawa, Kendo
collection PubMed
description Fifty‐eight patients with chronic hepatitis C were followed for more than 7 years. Of them, 10 patients were found to develop hepatocellular carcinoma, 14 to develop liver cirrhosis, 30 to sustain chronic hepatitis, and 4 to show subsidence of hepatitis. Antibody to hepatitis C virus (anti‐HCV) disappeared from the 4 patients whose hepatitis subsided, but it persisted in the remaining 54 patients. The mean titer of anti‐HCV was almost the same at the stages of chronic hepatitis and of cancer in the 10 patients who developed hepatocellular carcinoma. These results indicate that chronic infection of hepatitis C virus may lead to hepatocellular carcinoma.
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spelling pubmed-59179922018-05-11 Transition of Antibody to Hepatitis C Virus from Chronic Hepatitis to Hepatocellular Carcinoma Kiyosawa, Kendo Tanaka, Eiji Sodeyama, Takeshi Furuta, Kiyoshi Usuda, Seiichi Yousuf, Muhammad Furuta, Seiichi Jpn J Cancer Res Rapid Communication Fifty‐eight patients with chronic hepatitis C were followed for more than 7 years. Of them, 10 patients were found to develop hepatocellular carcinoma, 14 to develop liver cirrhosis, 30 to sustain chronic hepatitis, and 4 to show subsidence of hepatitis. Antibody to hepatitis C virus (anti‐HCV) disappeared from the 4 patients whose hepatitis subsided, but it persisted in the remaining 54 patients. The mean titer of anti‐HCV was almost the same at the stages of chronic hepatitis and of cancer in the 10 patients who developed hepatocellular carcinoma. These results indicate that chronic infection of hepatitis C virus may lead to hepatocellular carcinoma. Blackwell Publishing Ltd 1990-11 /pmc/articles/PMC5917992/ /pubmed/2176199 http://dx.doi.org/10.1111/j.1349-7006.1990.tb02517.x Text en
spellingShingle Rapid Communication
Kiyosawa, Kendo
Tanaka, Eiji
Sodeyama, Takeshi
Furuta, Kiyoshi
Usuda, Seiichi
Yousuf, Muhammad
Furuta, Seiichi
Transition of Antibody to Hepatitis C Virus from Chronic Hepatitis to Hepatocellular Carcinoma
title Transition of Antibody to Hepatitis C Virus from Chronic Hepatitis to Hepatocellular Carcinoma
title_full Transition of Antibody to Hepatitis C Virus from Chronic Hepatitis to Hepatocellular Carcinoma
title_fullStr Transition of Antibody to Hepatitis C Virus from Chronic Hepatitis to Hepatocellular Carcinoma
title_full_unstemmed Transition of Antibody to Hepatitis C Virus from Chronic Hepatitis to Hepatocellular Carcinoma
title_short Transition of Antibody to Hepatitis C Virus from Chronic Hepatitis to Hepatocellular Carcinoma
title_sort transition of antibody to hepatitis c virus from chronic hepatitis to hepatocellular carcinoma
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917992/
https://www.ncbi.nlm.nih.gov/pubmed/2176199
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02517.x
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