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Synergistic Effect in Culture of Bleomycin‐group Antibiotics and N‐Solanesyl‐N, N’‐bis(3,4‐dimethoxybenzyl)ethylenediamine, a Synthetic Isoprenoid

Like bleomycin and peplomycin, libromycin, a newly developed bleomycin‐group antibiotic, was potentiated 130‐fold against Chinese hamster V79 cells (V79/S) and 47‐fold against its multidrug‐resistant mutant (V79/ADM) by N‐solanesyl‐N, N’‐bis(3,4‐dimethoxybenzyl)ethylenediamine (SDB‐ethylenediamine)...

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Detalles Bibliográficos
Autores principales: Tomida, Akihiro, Suzuki, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917996/
https://www.ncbi.nlm.nih.gov/pubmed/1702416
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02532.x