Cargando…

Promoting Effect of the Peroxisome Proliferator, Clofibrate, but Not Di(2‐ethylhexyl)phthalate, on Urinary Bladder Carcinogenesis in F344 Rats Initiated by N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine

The modifying potential of clofibrate and di(2‐ethylhexyl)phthalate (DEHP) on second stage, N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine (BBN)‐initiated urinary bladder carcinogenesis was investigated in male F344 rats, using a uracil‐accelerated transitional cell proliferation model. Six‐week‐old animals...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hagiwara, Akihiro, Tamano, Seiko, Ogiso, Tadashi, Asakawa, Emiko, Fukushima, Shoji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1990
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918008/ https://www.ncbi.nlm.nih.gov/pubmed/2125992 http://dx.doi.org/10.1111/j.1349-7006.1990.tb02684.x

Ejemplares similares

Synergism of Environmental Carcinogens and Promoters on Bladder Cancer Development Initiated by N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine in F344 Rats
por: Ono, Satoko, et al.
Publicado: (1992)

Strain Differences in N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine Bladder Carcinogenesis in Rats
por: Nakanowatari, Jun‐ichi, et al.
Publicado: (1988)

Effects of promoters on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in the rat.
por: Ito, N, et al.
Publicado: (1983)

Time‐ and Dose‐dependent Induction of Invasive Urinary Bladder Cancers by N‐Ethyl‐N‐(4‐hydroxybutyl)nitrosamine in B6C3F(1) Mice
por: Tamano, Seiko, et al.
Publicado: (1991)

No Promoting Effect of Ethyl Tertiary-butyl Ether (ETBE) on Rat Urinary Bladder Carcinogenesis Initiated with N-Butyl-N-(4-hydroxybutyl)nitrosamine
por: Hagiwara, Akihiro, et al.
Publicado: (2013)

The interaction of arsenic and N-butyl-N-(4-hydroxybutyl)nitrosamine on urothelial carcinogenesis in mice
por: Dai, Yuan-Chang, et al.
Publicado: (2017)

Chemopreventive Effects of Bovine Lactoferrin on N‐Butyl‐N‐(4‐ hydroxybutyl)nitrosamine‐induced Rat Bladder Carcinogenesis
por: Masuda, Chikayoshi, et al.
Publicado: (2000)

Summation Effects of Uracil and Other Promoters on Epithelial Lesion Development in the F344 Rat Urinary Bladder Initiated by N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine
por: de Camargo, João Lauro Viana, et al.
Publicado: (1991)

Effect of Schistosoma haematobium and N-butyl-N-(4-hydroxybutyl)nitrosamine on the development of urothelial neoplasia in the baboon
por: Hicks, R. M., et al.
Publicado: (1980)

Loss of Heterozygosity in (Lewis×F344)F(1) Rat Urinary Bladder Tumors Induced with N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine Followed by Dimethylarsinic Acid or Sodium L‐Ascorbate
por: Chen, Tianxin, et al.
Publicado: (1999)

Knockout of phospholipase Cε attenuates N-butyl-N-(4-hydroxybutyl) nitrosamine-induced bladder tumorigenesis
por: JIANG, TAIMAO, et al.
Publicado: (2016)

DNA cytophotometric and histological analysis of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced precancerous lesions of the bladder urothelium
por: Dahm, Hans Helmut, et al.
Publicado: (2016)

Inhibitory Effect of Tomato Juice on Rat Urinary Bladder Carcinogenesis after N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine Initiation
por: Okajima, Eijiro, et al.
Publicado: (1998)

Anti‐promoting Effect of Nordihydroguaiaretic Acid on N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine and Sodium Saccharin‐induced Rat Urinary Bladder Carcinogenesis
por: Yu, Akinori, et al.
Publicado: (1992)

Teratogenicity of di(2-ethylhexyl) phthalate (DEHP) and di-n-butyl phthalate (DBP) in mice.
por: Shiota, K, et al.
Publicado: (1982)

Renal Pelvic Carcinoma which Shows Metastatic Potential to Distant Organs, Induced by N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine in NON/Shi Mice
por: Murai, Takashi, et al.
Publicado: (1991)

Chemopreventive Effects of a Flavonoid Antioxidant Silymarin on N‐Butyl‐N‐(4‐ hydroxybutyl)nitrosamine‐induced Urinary Bladder Carcinogenesis in Male ICR Mice
por: Vinh, Pham Quang, et al.
Publicado: (2002)

Low Susceptibility of Long‐Evans Cinnamon Rats to N‐Butyl‐N‐(4‐hydroxybutyl)‐nitrosamine‐induced Urinary Bladder Carcinogenesis and Inhibitory Effect of Urinary Copper
por: Chone, Yoshifumi, et al.
Publicado: (2000)

Mutagenicity of the peroxisome proliferators clofibrate, Wyeth 14,643 and di-2-ethylhexyl phthalate in the lacZ plasmid-based transgenic mouse mutation assay
por: Boerrigter, Michaël ETI
Publicado: (2004)

Detection of γ-H2AX, a Biomarker for DNA Double-strand Breaks, in Urinary Bladders of N -Butyl- N -(4-Hydroxybutyl)-Nitrosamine-Treated Rats
por: Toyoda, Takeshi, et al.
Publicado: (2013)

Chemopreventive Efficacy of Piroxicam Administered Alone or in Combination with Lycopene and β‐Carotene on the Development of Rat Urinary Bladder Carcinoma after A N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine Treatment
por: Okajima, Eijiro, et al.
Publicado: (1997)

p53 and H‐ras Mutations and Microsatellite Instability in Renal Pelvic Carcinomas of NON/Shi Mice Treated with N‐Butyl‐N‐(4‐hydroxybutyl)‐nitrosamine: Different Genetic Alteration from Urinary Bladder Carcinoma
por: Gen, Hiroyuki, et al.
Publicado: (2001)

Plasminogen activator inhibitor-2 (PAI-2) overexpression supports bladder cancer development in PAI-1 knockout mice in N-butyl-N- (4-hydroxybutyl)-nitrosamine- induced bladder cancer mouse model
por: Furuya, Hideki, et al.
Publicado: (2020)

Lack of Carcinogenicity of Quercetin in F344/DuCrj Rats
por: Ito, Nobuyuki, et al.
Publicado: (1989)

Forestomach Neoplasm Induction in F344/DuCrj Rats and B6C3F(1) Mice Exposed to Sesamol
por: Tamano, Seiko, et al.
Publicado: (1992)

Thyroid Disruption by Di-n-Butyl Phthalate (DBP) and Mono-n-Butyl Phthalate (MBP) in Xenopus laevis
por: Shen, Ouxi, et al.
Publicado: (2011)

Is peroxisome proliferation an obligatory precursor step in the carcinogenicity of di(2-ethylhexyl)phthalate (DEHP)?
por: Melnick, R L
Publicado: (2001)

Comparison of hepatic peroxisome proliferative effect and its implication for hepatocarcinogenicity of phthalate esters, di(2-ethylhexyl) phthalate, and di(2-ethylhexyl) adipate with a hypolipidemic drug.
por: Reddy, J K, et al.
Publicado: (1986)

Peroxisome proliferation due to di(2-ethylhexyl) phthalate (DEHP): species differences and possible mechanisms.
por: Elcombe, C R, et al.
Publicado: (1986)

Carcinogenicity of Captafol in F344/DuCrj Rats
por: Tamano, Seiko, et al.
Publicado: (1990)

Topical and systemic immunoreaction triggered by intravesical chemotherapy in an N-butyl-N-(4-hydroxybutyl) nitorosamine induced bladder cancer mouse model
por: Hori, Shunta, et al.
Publicado: (2017)

Decreased Serum Free Testosterone in Workers Exposed to High Levels of Di-n-butyl Phthalate (DBP) and Di-2-ethylhexyl Phthalate (DEHP): A Cross-Sectional Study in China
por: Pan, Guowei, et al.
Publicado: (2006)

Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome proliferator-activated receptor alpha: a review
por: Ito, Yuki, et al.
Publicado: (2019)

Significant Increase of 8‐Hydroxydeoxyguanosine in Liver DNA of Rats Following Short‐term Exposure to the Peroxisome Proliferators Di(2‐ethylhexyl)phthalate and Di(2‐ethylhexyl)adipate
por: Takagi, Atsuya, et al.
Publicado: (1990)

The in vitro serum protein-binding characteristics of bis-(2-ethylhexyl) phthalate and its principal metabolite, mono-(2-ethylhexyl) phthalate.
por: Griffiths, W C, et al.
Publicado: (1988)

Tumorigenicity of the hypolipidaemic peroxisome proliferator ethyl-alpha-p-chlorophenoxyisobutyrate (clofibrate) in rats.
por: Reddy, J. K., et al.
Publicado: (1979)

Effect of a Large Dose of Di (2-ethylhexyl) phthalate (DEHP) on Hepatic Peroxisome in Cynomolgus Monkeys (Macaca Fascicularis)
por: Satake, Shigeru, et al.
Publicado: (2010)

The Induction of Bladder Tumors in F344 Rats by Intravesicular Administration of Some Nitrosamines
por: Thomas, Barbara J., et al.
Publicado: (1988)

Bio-Source of di-n-butyl phthalate production by filamentous fungi
por: Tian, Congkui, et al.
Publicado: (2016)

Adsorption kinetics and mechanism of di‐n‐butyl phthalate by Leuconostoc mesenteroides
por: Zhao, Lili, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_65q8u11t7s91khf9b5l6ve10uh