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Increase in the Level of P‐Glycoprotein mRNA Expression in Multidrug‐resistant K562 Cell Lines Treated with Sodium Butyrate Is Not Accompanied with Erythroid Differentiation

We examined the effects of hemin, sodium butyrate and mitomycin C on levels of P‐glycoprotein mRNA in human myelogenous K562 cells by northern blot analysis. After treatment with sodium butyrate a dose‐dependent increase of P‐glycoprotein mRNA expression was observed in the adriamycin‐resistant K562...

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Detalles Bibliográficos
Autores principales:	Shibata, Hiroyuki, Kanamaru, Ryunosuke, Sato, Toshiaki, Ishioka, Chikashi, Konishi, Yukari, Ishikawa, Akira, Wakui, Akira, Tsuruo, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1990
Materias:	Rapid Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918010/ https://www.ncbi.nlm.nih.gov/pubmed/1980493 http://dx.doi.org/10.1111/j.1349-7006.1990.tb02681.x

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