Fv‐1 Restriction of Endogenous Feline C‐Type RD114 Virus Genome Phenotypically Mixed with Ecotropic Murine Leukemia Viruses

Endogenous feline leukemia RD114 virus genome rendered capable of infecting mouse cells by phenotypic mixing with an ecotropic murine leukemia virus (MuLV) exhibited the Fv‐1 restriction pattern of the ecotropic murine virus. However, RD114 genomes phenotypically mixed with ecotropic MuLV showed one...

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Detalles Bibliográficos
Autores principales: Kakimi, Kazuhiro, Kishida, Yoshiko, Higuchi, Ikuko, Kiyomasu, Takahiro, Sakai, Hiroyuki, Shibata, Riri, Yanagawa, Shin‐ichiro, Adachi, Akio, Ishimoto, Akinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918088/
https://www.ncbi.nlm.nih.gov/pubmed/2168865
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02643.x
Descripción
Sumario:Endogenous feline leukemia RD114 virus genome rendered capable of infecting mouse cells by phenotypic mixing with an ecotropic murine leukemia virus (MuLV) exhibited the Fv‐1 restriction pattern of the ecotropic murine virus. However, RD114 genomes phenotypically mixed with ecotropic MuLV showed one‐hit dose‐response kinetics, even when titrated with murine cells with the restricted Fv‐1 phenotype.

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