Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis

The neurodegenerative disease multiple sclerosis (MS) is pathologically characterized by the massive influx of immune cells into the central nervous system. This contributes to demyelination and axonal damage which causes symptoms such as motor and cognitive dysfunctions. The migration of leukocytes...

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Detalles Bibliográficos
Autores principales: Chrobok, Navina L., Bol, John G. J. M., Jongenelen, Cornelis A., Brevé, John J. P., El Alaoui, Said, Wilhelmus, Micha M. M., Drukarch, Benjamin, van Dam, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918173/
https://www.ncbi.nlm.nih.gov/pubmed/29689097
http://dx.doi.org/10.1371/journal.pone.0196433

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