Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation

Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden cardiac death in young individuals. A potential role of mtDNA mutations in HCM is known. However, the underlying molecular mechanisms linking mtDNA mutations to HCM remain poorly understood due to lack of cell and animal models. He...

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Detalles Bibliográficos
Autores principales: Li, Shishi, Pan, Huaye, Tan, Chao, Sun, Yaping, Song, Yanrui, Zhang, Xuan, Yang, Wei, Wang, Xuexiang, Li, Dan, Dai, Yu, Ma, Qiang, Xu, Chenming, Zhu, Xufen, Kang, Lijun, Fu, Yong, Xu, Xuejun, Shu, Jing, Zhou, Naiming, Han, Feng, Qin, Dajiang, Huang, Wendong, Liu, Zhong, Yan, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918198/
https://www.ncbi.nlm.nih.gov/pubmed/29456182
http://dx.doi.org/10.1016/j.stemcr.2018.01.013

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