Cargando…

GDNF/GFRα1 Complex Abrogates Self-Renewing Activity of Cortical Neural Precursors Inducing Their Differentiation

The balance between factors leading to proliferation and differentiation of cortical neural precursors (CNPs) determines the correct cortical development. In this work, we show that GDNF and its receptor GFRα1 are expressed in the neocortex during the period of cortical neurogenesis. We show that th...

Descripción completa

Detalles Bibliográficos
Autores principales: Bonafina, Antonela, Fontanet, Paula Aldana, Paratcha, Gustavo, Ledda, Fernanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918270/
https://www.ncbi.nlm.nih.gov/pubmed/29478900
http://dx.doi.org/10.1016/j.stemcr.2018.01.019