Cargando…

GDNF/GFRα1 Complex Abrogates Self-Renewing Activity of Cortical Neural Precursors Inducing Their Differentiation

The balance between factors leading to proliferation and differentiation of cortical neural precursors (CNPs) determines the correct cortical development. In this work, we show that GDNF and its receptor GFRα1 are expressed in the neocortex during the period of cortical neurogenesis. We show that th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bonafina, Antonela, Fontanet, Paula Aldana, Paratcha, Gustavo, Ledda, Fernanda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918270/ https://www.ncbi.nlm.nih.gov/pubmed/29478900 http://dx.doi.org/10.1016/j.stemcr.2018.01.019

Ejemplares similares

RET-independent signaling by GDNF ligands and GFRα receptors
por: Ibáñez, Carlos F., et al.
Publicado: (2020)

Deciphering New Players in the Neurogenic Adult Hippocampal Niche
por: Bonafina, Antonela, et al.
Publicado: (2020)

Architecture and regulation of a GDNF-GFRα1 synaptic adhesion assembly
por: Houghton, F. M., et al.
Publicado: (2023)

Sprouty4 Is an Endogenous Negative Modulator of TrkA Signaling and Neuronal Differentiation Induced by NGF
por: Alsina, Fernando C., et al.
Publicado: (2012)

Negative Regulation of Receptor Tyrosine Kinase (RTK) Signaling: A Developing Field
por: Ledda, Fernanda, et al.
Publicado: (2007)

Assembly of Neuronal Connectivity by Neurotrophic Factors and Leucine-Rich Repeat Proteins
por: Ledda, Fernanda, et al.
Publicado: (2016)

TGFβ induces GDNF responsiveness in neurons by recruitment of GFRα1 to the plasma membrane
por: Peterziel, H., et al.
Publicado: (2002)

Simultaneous Detection of Both GDNF and GFRα1 Expression Patterns in the Mouse Central Nervous System
por: Ortega-de San Luis, Clara, et al.
Publicado: (2016)

Adult medial habenula neurons require GDNF receptor GFRα1 for synaptic stability and function
por: Fernández-Suárez, Diana, et al.
Publicado: (2021)

Data on in vivo phenotypes of GFRα1-positive spermatogonia stimulated by interstitial GDNF signals in mouse testes
por: Uchida, Aya, et al.
Publicado: (2016)

Induction of GDNF and GFRα-1 Following AAV1-Rheb(S16H) Administration in the Hippocampus in vivo
por: Yun, Dongyoung, et al.
Publicado: (2020)

Mechanisms That Modulate and Diversify BDNF Functions: Implications for Hippocampal Synaptic Plasticity
por: De Vincenti, Ana Paula, et al.
Publicado: (2019)

Mutation and deletion analysis of GFRα-1, encoding the co-receptor for the GDNF/RET complex, in human brain tumours
por: Gimm, O, et al.
Publicado: (1999)

Role of GDNF, GFRα1 and GFAP in a Bifidobacterium-Intervention Induced Mouse Model of Intestinal Neuronal Dysplasia
por: Liu, Wei, et al.
Publicado: (2022)

GDNF promotes tubulogenesis of GFRα1-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase
por: Popsueva, Anna, et al.
Publicado: (2003)

Sprouty4 at the crossroads of Trk neurotrophin receptor signaling suppression by glucocorticoids
por: Ferrero Restelli, Facundo, et al.
Publicado: (2023)

Zebrafish GDNF and its co-receptor GFRα1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitro
por: Saarenpää, Tuulia, et al.
Publicado: (2017)

APE1 Promotes Pancreatic Cancer Proliferation through GFRα1/Src/ERK Axis-Cascade Signaling in Response to GDNF
por: Choi, Yoo-Duk, et al.
Publicado: (2020)

Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRα1 or RET Impairs Normal Cerebellar Motor Learning
por: Sergaki, Maria Christina, et al.
Publicado: (2017)

Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFRα1 for Specific Infection of Breast Cancer Cells
por: Hall, Bonnie L., et al.
Publicado: (2020)

Tiam1 as a Signaling Mediator of Nerve Growth Factor-Dependent Neurite Outgrowth
por: Shirazi Fard, Shahrzad, et al.
Publicado: (2010)

A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing
por: Adams, Sarah E., et al.
Publicado: (2021)

Peripheral injury of pelvic visceral sensory nerves alters GFRα (GDNF family receptor alpha) localization in sensory and autonomic pathways of the sacral spinal cord
por: Forrest, Shelley L., et al.
Publicado: (2015)

Effects of gestational inflammation on age-related cognitive decline and hippocampal Gdnf-GFRα1 levels in F1 and F2 generations of CD-1 Mice
por: Luo, Bao-Ling, et al.
Publicado: (2023)

Muscle stem cell renewal suppressed by Gas1 can be reversed by GDNF in mice
por: Li, Liangji, et al.
Publicado: (2019)

microRNA regulation of neural precursor self-renewal and differentiation
por: Hudish, Laura I, et al.
Publicado: (2014)

Dl-3-n-Butylphthalide Reduces Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion Through GDNF/GFRα1/Ret Signaling Preventing Hippocampal Neuron Apoptosis
por: Li, Wenxian, et al.
Publicado: (2019)

Structural Basis for Self-Renewal of Neural Progenitors in Cortical Neurogenesis
por: Shioi, Go, et al.
Publicado: (2009)

Prognostic significance of the expression of GFRα1, GFRα3 and Syndecan-3, proteins binding ARTEMIN, in mammary carcinoma
por: Wu, Zheng-Sheng, et al.
Publicado: (2013)

Pre-α-pro-GDNF and Pre-β-pro-GDNF Isoforms Are Neuroprotective in the 6-hydroxydopamine Rat Model of Parkinson's Disease
por: Penttinen, Anna-Maija, et al.
Publicado: (2018)

Purification of GFRα1+ and GFRα1– Spermatogonial Stem Cells Reveals a Niche-Dependent Mechanism for Fate Determination
por: Garbuzov, Alina, et al.
Publicado: (2018)

Functional Differences between GDNF-Dependent and FGF2-Dependent Mouse Spermatogonial Stem Cell Self-Renewal
por: Takashima, Seiji, et al.
Publicado: (2015)

Stable STIM1 Knockdown in Self-Renewing Human Neural Precursors Promotes Premature Neural Differentiation
por: Gopurappilly, Renjitha, et al.
Publicado: (2018)

Novel circGFRα1 Promotes Self-Renewal of Female Germline Stem Cells Mediated by m(6)A Writer METTL14
por: Li, Xiaoyong, et al.
Publicado: (2021)

Disruption of specific GDNF receptor subtype signaling impairs cortical neuronal survival in Alzheimer’s brains
por: Konishi, Yoshihiro, et al.
Publicado: (2012)

Improved estimation of glomerular filtration rate (GFR) by comparison of eGFR(cystatin C) and eGFR(creatinine)
por: Grubb, Anders, et al.
Publicado: (2012)

Spermatogonial Stem Cell Numbers Are Reduced by Transient Inhibition of GDNF Signaling but Restored by Self-Renewing Replication when Signaling Resumes
por: Parker, Nicole, et al.
Publicado: (2021)

Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells
por: Akhtar, Aslam Abbasi, et al.
Publicado: (2018)

The Future of GDNF in Parkinson's Disease
por: Manfredsson, Fredric P., et al.
Publicado: (2020)

Photoreceptor preservation induced by intravitreal controlled delivery of GDNF and GDNF/melatonin in rhodopsin knockout mice
por: García-Caballero, Cristina, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_imqr4vmnalf2mgv3id4r5m4r02