Induction of Renal Cell Tumors in Rats and Mice, and Enhancement of Hepatocellular Tumor Development in Mice after Long‐term Hydroquinone Treatment

Hydroquinone (HQ) was administered to F344 rats and B6C3F(1) mice of both sexes at a level of 0.8% in the diet for two years. This treatment induced renal tubular hyperplasia as well as adenomas, predominantly in males of both species, and was associated with chronic nephropathy in rats. In addition...

Descripción completa

Detalles Bibliográficos
Autores principales: Shibata, Masa‐Aki, Hirose, Masao, Tanaka, Hikaru, Asakawa, Emiko, Shirai, Tomoyuki, Ito, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918322/
https://www.ncbi.nlm.nih.gov/pubmed/1752780
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01783.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918322/
https://www.ncbi.nlm.nih.gov/pubmed/1752780
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01783.x

Ejemplares similares