The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells

Self-renewal and differentiation of adult stem cells are tightly regulated partly through configuration of chromatin structure by chromatin remodelers. Using knockout mice, we here demonstrate that bromodomain PHD finger transcription factor (BPTF), a component of the nucleosome remodeling factor (N...

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Detalles Bibliográficos
Autores principales: Xu, Bowen, Cai, Ling, Butler, Jason M., Chen, Dongliang, Lu, Xiongdong, Allison, David F., Lu, Rui, Rafii, Shahin, Parker, Joel S., Zheng, Deyou, Wang, Gang Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918338/
https://www.ncbi.nlm.nih.gov/pubmed/29456179
http://dx.doi.org/10.1016/j.stemcr.2018.01.020

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