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Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models
In vivo studies of human brain cellular function face challenging ethical and practical difficulties. Animal models are typically used but display distinct cellular differences. One specific example is astrocytes, recently recognized for contribution to neurological diseases and a link to the geneti...
Autores principales: | Lundin, Anders, Delsing, Louise, Clausen, Maryam, Ricchiuto, Piero, Sanchez, José, Sabirsh, Alan, Ding, Mei, Synnergren, Jane, Zetterberg, Henrik, Brolén, Gabriella, Hicks, Ryan, Herland, Anna, Falk, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918339/ https://www.ncbi.nlm.nih.gov/pubmed/29456185 http://dx.doi.org/10.1016/j.stemcr.2018.01.021 |
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