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Exosome-Mediated Benefits of Cell Therapy in Mouse and Human Models of Duchenne Muscular Dystrophy

Genetic deficiency of dystrophin leads to disability and premature death in Duchenne muscular dystrophy (DMD), affecting the heart as well as skeletal muscle. Here, we report that clinical-stage cardiac progenitor cells, known as cardiosphere-derived cells (CDCs), improve cardiac and skeletal myopat...

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Detalles Bibliográficos
Autores principales: Aminzadeh, Mark A., Rogers, Russell G., Fournier, Mario, Tobin, Rachel E., Guan, Xuan, Childers, Martin K., Andres, Allen M., Taylor, David J., Ibrahim, Ahmed, Ding, Xiangming, Torrente, Angelo, Goldhaber, Joshua M., Lewis, Michael, Gottlieb, Roberta A., Victor, Ronald A., Marbán, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918344/
https://www.ncbi.nlm.nih.gov/pubmed/29478899
http://dx.doi.org/10.1016/j.stemcr.2018.01.023