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Exosome-Mediated Benefits of Cell Therapy in Mouse and Human Models of Duchenne Muscular Dystrophy
Genetic deficiency of dystrophin leads to disability and premature death in Duchenne muscular dystrophy (DMD), affecting the heart as well as skeletal muscle. Here, we report that clinical-stage cardiac progenitor cells, known as cardiosphere-derived cells (CDCs), improve cardiac and skeletal myopat...
Autores principales: | Aminzadeh, Mark A., Rogers, Russell G., Fournier, Mario, Tobin, Rachel E., Guan, Xuan, Childers, Martin K., Andres, Allen M., Taylor, David J., Ibrahim, Ahmed, Ding, Xiangming, Torrente, Angelo, Goldhaber, Joshua M., Lewis, Michael, Gottlieb, Roberta A., Victor, Ronald A., Marbán, Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918344/ https://www.ncbi.nlm.nih.gov/pubmed/29478899 http://dx.doi.org/10.1016/j.stemcr.2018.01.023 |
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