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Effects of the Tumor Inhibitor IKP‐104, a 4(lH)‐Pyridinone Derivative, on Cytoskeletal Microtuhules of Cultured Tumor Cells

The effects of IKP‐104, a 4(lH)‐pyridinone derivative, on the mitotic profile and cytoskeletal microtubule dynamics of cultured B16 melanoma cells were examined in order to investigate the mechanism of its antitumor activity. The exposure to IKP‐104 caused accumulation of cells in abnormal metaphase...

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Detalles Bibliográficos
Autores principales:	Mizuhashi, Fukutaro, Murata, Kyoji, Kitagaki, Tadaharu, Isao, Isao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1991
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918355/ https://www.ncbi.nlm.nih.gov/pubmed/1778768 http://dx.doi.org/10.1111/j.1349-7006.1991.tb01818.x

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