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Rapid Induction of Endometrial Carcinoma in ICR Mice Treated with N‐Methyl‐N‐nitrosourea and 17β‐Estradiol

The present study was undertaken to develop an animal model for endometrial neoplasms. A total of 107 female ICR mice, 10 weeks of age, were used and treated as follows: Group 1 (31 mice) was given intravaginal instillation of N‐methyl‐N‐nitrosourea (MNU) solution (1 mg/100 g body wt.) once a week f...

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Detalles Bibliográficos
Autores principales:	Niwa, Kenji, Tanaka, Takuji, Mori, Hideki, Yokoyama, Yasuhiro, Furui, Tatsuro, Mori, Hidehiro, Teruhiko, Teruhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1991
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918362/ https://www.ncbi.nlm.nih.gov/pubmed/1778763 http://dx.doi.org/10.1111/j.1349-7006.1991.tb01811.x

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