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Induction of Aberrant Crypt Foci in the Large Intestine of F344 Rats by Oral Administration of 2‐Amino‐l‐methyl‐6‐phenylimidazo[4,5‐b]pyridine

Carcinogenicity of 2‐amino‐l‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) to rat colon was investigated using the appearance of colonic aberrant crypt (AC), a preneoplastic lesion, as a marker. The number of AC foci per colon at experimental week 4 was 1.3 ± 0.8; almost half the level of AC foci ind...

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Detalles Bibliográficos
Autores principales:	Takahashi, Satoru, Ogawa, Kumiko, Ohshima, Hiroshi, Esumi, Hiroyasu, Ito, Nobuyuki, Sugimura, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1991
Materias:	Rapid Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918369/ https://www.ncbi.nlm.nih.gov/pubmed/1900817 http://dx.doi.org/10.1111/j.1349-7006.1991.tb01819.x

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