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Topoisomerase Inhibitors Have Potent Differentiation‐inducing Activity for Human and Mouse Myeloid Leukemia Cells

DNA topoisomerase inhibitors, camptothecin and 4′‐demethylepipodophyllotoxin ethylidene‐jS‐D‐glucoside (VP16) had strong differentiation‐inducing activity for all five kinds of leukemia cells examined (human HL60, U937, ML1, and K562 cells and mouse Ml cells) as judged from measurements of various d...

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Detalles Bibliográficos
Autores principales: Nakaya, Kazuyasu, Chou, Sawako, Kaneko, Motohisa, Nakamura, Yasuharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918380/
https://www.ncbi.nlm.nih.gov/pubmed/1848545
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01827.x