Tumor Localization and in vivo Antitumor Activity of the Immunoconjugate Composed of Anti‐human Colon Cancer Monoclonal Antibody and Mitomycin C‐Dextran Conjugate

The tissue distribution and in vivo antitumor activity of a novel monoclonal antibody‐mitomycin C conjugate (A7‐MMCD) composed of anti‐human MAb A7 and MMC‐dextran conjugate were investigated using tumor‐bearing mice. A7‐MMCD was prepared via an anionic dextran intermediate for the purpose of keepin...

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Detalles Bibliográficos
Autores principales: Noguchi, Akinori, Takahashi, Toshio, Yamaguchi, Toshiharu, Kitamura, Kazuya, Takakura, Yoshinobu, Hashida, Mitsuru, Sezaki, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918381/
https://www.ncbi.nlm.nih.gov/pubmed/1706329
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01832.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918381/
https://www.ncbi.nlm.nih.gov/pubmed/1706329
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01832.x

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