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Tumor Localization and in vivo Antitumor Activity of the Immunoconjugate Composed of Anti‐human Colon Cancer Monoclonal Antibody and Mitomycin C‐Dextran Conjugate

The tissue distribution and in vivo antitumor activity of a novel monoclonal antibody‐mitomycin C conjugate (A7‐MMCD) composed of anti‐human MAb A7 and MMC‐dextran conjugate were investigated using tumor‐bearing mice. A7‐MMCD was prepared via an anionic dextran intermediate for the purpose of keepin...

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Detalles Bibliográficos
Autores principales:	Noguchi, Akinori, Takahashi, Toshio, Yamaguchi, Toshiharu, Kitamura, Kazuya, Takakura, Yoshinobu, Hashida, Mitsuru, Sezaki, Hitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1991
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918381/ https://www.ncbi.nlm.nih.gov/pubmed/1706329 http://dx.doi.org/10.1111/j.1349-7006.1991.tb01832.x

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