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Tumor Localization and in vivo Antitumor Activity of the Immunoconjugate Composed of Anti‐human Colon Cancer Monoclonal Antibody and Mitomycin C‐Dextran Conjugate
The tissue distribution and in vivo antitumor activity of a novel monoclonal antibody‐mitomycin C conjugate (A7‐MMCD) composed of anti‐human MAb A7 and MMC‐dextran conjugate were investigated using tumor‐bearing mice. A7‐MMCD was prepared via an anionic dextran intermediate for the purpose of keepin...
Autores principales: | Noguchi, Akinori, Takahashi, Toshio, Yamaguchi, Toshiharu, Kitamura, Kazuya, Takakura, Yoshinobu, Hashida, Mitsuru, Sezaki, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1991
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918381/ https://www.ncbi.nlm.nih.gov/pubmed/1706329 http://dx.doi.org/10.1111/j.1349-7006.1991.tb01832.x |
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