Cargando…

Tumor Localization and in vivo Antitumor Activity of the Immunoconjugate Composed of Anti‐human Colon Cancer Monoclonal Antibody and Mitomycin C‐Dextran Conjugate

The tissue distribution and in vivo antitumor activity of a novel monoclonal antibody‐mitomycin C conjugate (A7‐MMCD) composed of anti‐human MAb A7 and MMC‐dextran conjugate were investigated using tumor‐bearing mice. A7‐MMCD was prepared via an anionic dextran intermediate for the purpose of keepin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Noguchi, Akinori, Takahashi, Toshio, Yamaguchi, Toshiharu, Kitamura, Kazuya, Takakura, Yoshinobu, Hashida, Mitsuru, Sezaki, Hitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1991
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918381/ https://www.ncbi.nlm.nih.gov/pubmed/1706329 http://dx.doi.org/10.1111/j.1349-7006.1991.tb01832.x

Ejemplares similares

Comparative Pharmacokinetic Properties of Murine Monoclonal Antibody A7 Modified with Neocarzinostatin, Dextran and Polyethylene Glycol
por: Takashina, Ken‐ichiro, et al.
Publicado: (1991)

Follow‐up Study of Patients Treated with Monoclonal Antibody‐Drug Conjugate: Report of 77 Cases with Colorectal Cancer
por: Takahashi, Toshio, et al.
Publicado: (1993)

Efficacy and Specificity of a Monoclonal Antibody‐Drug Conjugate in Chemotherapy by Intratumoral Injection
por: Kitamura, Kazuya, et al.
Publicado: (1992)

Enhanced Tumor Localization of Monoclonal Antibody by Treatment with Kininase II Inhibitor and Angiotensin II
por: Noguchi, Akinori, et al.
Publicado: (1992)

Production, Binding and Cytotoxicity of Human/Mouse Chimeric Monoclonal Antibody‐Neocarzinostatin Conjugate
por: Yamaguchi, Toshiharu, et al.
Publicado: (1993)

Muramyl dipeptide CD10 monoclonal antibody immunoconjugates inhibited acute leukemia in nude mice
por: Wang, Yilin, et al.
Publicado: (2023)

Targeted Therapy With Immunoconjugates for Multiple Myeloma
por: Bruins, Wassilis S. C., et al.
Publicado: (2020)

Decreased Renal Accumulation of Biotinylated Chimeric Monoclonal Antibody‐Neocarzinostatin Conjugate after Administration of Avidin
por: Otsuji, Eigo, et al.
Publicado: (1997)

Biodistribution of Neocarzinostatin Conjugated to Chimeric Fab Fragments of the Monoclonal Antibody A7 in Nude Mice Bearing Human Pancreatic Cancer Xenografts
por: Otsuji, Eigo, et al.
Publicado: (1994)

Effect of Gelonin Immunoconjugate with Monoclonal Antibody MSN‐1 to Endometrial Adenocarcinoma on Antigen‐producing Tumor Cells in vivo
por: Kaneta, Yoshibumi, et al.
Publicado: (1998)

Xenogeneic monoclonal antibodies in the management of cancer: control of their in vivo immunogenicity and induction of specific unresponsiveness using an antibody-drug immunoconjugate.
por: Sivolapenko, G. B., et al.
Publicado: (1991)

Immunoconjugates for Osteosarcoma Therapy: Preclinical Experiences and Future Perspectives
por: Mercatelli, Daniele, et al.
Publicado: (2018)

Preparation and preclinical evaluation of humanised A33 immunoconjugates for radioimmunotherapy.
por: King, D. J., et al.
Publicado: (1995)

In vivo Efficacy of Neocarzinostatin Coupled with Fab Human/Mouse Chimeric Monoclonal Antibody A7 against Human Colorectal Cancer
por: Yamaguchi, Toshiharu, et al.
Publicado: (1994)

Immunoconjugates made of an anti-EGF receptor monoclonal antibody and type 1 ribosome-inactivating proteins from Saponaria ocymoides or Vaccaria pyramidata.
por: Di Massimo, A. M., et al.
Publicado: (1997)

Identification of Anti-gp41 Monoclonal Antibodies That Effectively Target Cytotoxic Immunoconjugates to Cells Infected with Human Immunodeficiency Virus, Type 1
por: Klug, Grant, et al.
Publicado: (2023)

Intratumoral Injection of an Adriamycin Immunoconjugate against Human Pancreatic Cancer Xenografts
por: Kondo, Yasuyuki, et al.
Publicado: (1995)

Cytotoxicity of Selenium Immunoconjugates against Triple Negative Breast Cancer Cells
por: Khandelwal, Soni, et al.
Publicado: (2018)

Enhanced Tumor Localization of Radiolabeled Fab Fragments of Monoclonal Antibody A7 in Nude Mice Bearing Human Pancreatic Carcinoma Xenografts
por: Otsuji, Eigo, et al.
Publicado: (1993)

Doxorubicin-incorporated polymeric micelles composed of dextran-b-poly(DL-lactide-co-glycolide) copolymer
por: Jeong, Young-Il, et al.
Publicado: (2011)

Photoimmunotherapy and biodistribution with an OC125-chlorin immunoconjugate in an in vivo murine ovarian cancer model.
por: Goff, B. A., et al.
Publicado: (1994)

Treatment of ovarian cancer with photodynamic therapy and immunoconjugates in a murine ovarian cancer model.
por: Goff, B. A., et al.
Publicado: (1996)

Site-Specifically Labeled Immunoconjugates for Molecular Imaging—Part 1: Cysteine Residues and Glycans
por: Adumeau, Pierre, et al.
Publicado: (2016)

Chemoenzymatic Strategy for the Synthesis of Site-Specifically Labeled Immunoconjugates for Multimodal PET and Optical Imaging
por: Zeglis, Brian M., et al.
Publicado: (2014)

Effectiveness of Polyclonal Antibody Immunoconjugate Treatment with Propamidine Isethionate for Amoebic Keratitis in Golden Hamsters
por: Ávila-Blanco, Manuel Enrique, et al.
Publicado: (2023)

Maleimidation of dextran and the application in designing a dextran–camptothecin conjugate
por: Zhu, Qiwen, et al.
Publicado: (2018)

Interaction of Fibrinogen with Dextran Sulfate
por: Sasaki, Susumu, et al.
Publicado: (1959)

Improved Admixture Vaccine of Fentanyl and Heroin Hapten Immunoconjugates: Antinociceptive Evaluation of Fentanyl-Contaminated Heroin
por: Hwang, Candy S., et al.
Publicado: (2018)

Blood–brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy
por: Galstyan, Anna, et al.
Publicado: (2019)

Diverse metabolic response of cancer cells treated with a (213)Bi-anti-EGFR-immunoconjugate
por: Feuerecker, Benedikt, et al.
Publicado: (2021)

Targeted photodestruction of human colon cancer cells using charged Dougherty chlorin(e6)immunoconjugates
por: Governatore, M Del, et al.
Publicado: (2000)

Alpha-Particle Emitting (213)Bi-Anti-EGFR Immunoconjugates Eradicate Tumor Cells Independent of Oxygenation
por: Wulbrand, Christian, et al.
Publicado: (2013)

Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with (89)Zr(4+): comparison with desferrioxamine-B
por: Ma, Michelle T., et al.
Publicado: (2015)

Design and Synthesis of Immunoconjugates and Development of an Indirect ELISA for Rapid Detection of 3, 5-Dinitrosalicyclic Acid Hydrazide
por: Shen, Yu-Dong, et al.
Publicado: (2008)

Enhancing the detection of Toxoplasma gondii via an anti-SAG1 scFv-alkaline phosphatase immunoconjugate
por: Hannachi, Emna, et al.
Publicado: (2019)

Antineoplastics/corticosteroids/immunoconjugates: Immune related adverse events and COVID-19-infection: 4 case reports
Publicado: (2020)

Synthesis and In Vitro Comparison of DOTA, NODAGA and 15-5 Macrocycles as Chelators for the (64)Cu-Labelling of Immunoconjugates
por: Maisonial-Besset, Aurélie, et al.
Publicado: (2022)

Combination of chemotherapy and immune checkpoint therapy by the immunoconjugates-based nanocomplexes synergistically improves therapeutic efficacy in SCLC
por: Tao, Zhang, et al.
Publicado: (2022)

Antitumor Activity of a Novel Double-Targeted System for Folate Receptor-Mediated Delivery of Mitomycin C
por: Xu, Yan, et al.
Publicado: (2020)

A Cooperative Randomized Study on Tegafur plus Mitomycin C versus Combined Tegafur and Uracil plus Mitomycin C in the Treatment of Advanced Gastric Cancer
por: Kurihara, Minoru, et al.
Publicado: (1991)

Cannot write session to /tmp/vufind_sessions/sess_vauo0ngqm3fapff257kluqv4hi