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Inhibitory Effect of 8‐Chloro‐cyclic Adenosine 3′,5′‐Monophosphate on Cell Growth of Gastric Carcinoma Cell Lines

A cAMP analogue, 8‐chloro‐cAMP (8‐Cl‐cAMP), selectively binds to site 1 receptor of type II regulatory subunit (RII) of cAMP‐dependent protein kinase. The effects of 8‐Cl‐cAMP on human gastric carcinoma cell lines were studied. Twenty μM 8‐CI‐cAMP clearly inhibited cell growth in six cell lines (TMK...

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Detalles Bibliográficos
Autores principales: Takanashi, Atsushi, Yasui, Wataru, Yoshida, Kazuhiro, Yokozaki, Hiroshi, Saito, Daizo, Abe, Kaoru, Urakami, Kenichi, Mild, Keizaburo, Tahara, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918396/
https://www.ncbi.nlm.nih.gov/pubmed/1850725
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01849.x