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Induction of Intestinal Adenocarcinomas by 2‐Amino‐l‐methyl‐6‐phenylimidazo‐[4,5‐b] pyridine in Nagase Analbuminemic Rats

2‐Amino‐l‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP), the most abundant mutagenic heterocyclic amine in cooked foods, was examined for carcinogenic potential using Nagase analbuminemic rats (NARs), which are sensitive to various carcinogens. The concentration of PhIP in the diet was 0.04% at the b...

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Detalles Bibliográficos
Autores principales: Ochiai, Masako, Ogawa, Kumiko, Wakabayashi, Keiji, Sugimura, Takashi, Nagase, Sumi, Esumi, Hiroyasu, Nagao, Minako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918438/
https://www.ncbi.nlm.nih.gov/pubmed/1904414
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01855.x