Enhancing Effect of a Choline–deficient Diet on Alterations of Hepatic Drug–metabolizing Enzymes in Hepatitis– and Hepatoma–predisposed Rats (LEC Rats)

Marked alterations of hepatic drug–metabolizing enzymes were observed in hepatitis– and hepatoma–predisposed rats (LEC rats) fed a choline–deficient diet. The diet enhanced the development of hepatitis with severe jaundice. The levels of two major classes of cytochrome P–450, P–450(PB) and P–450(MC)...

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Detalles Bibliográficos
Autores principales: Sugiyama, Toshihiro, Matsunaga, Mikako, Jain, Suresh K., Jain, Sadhana, Ikeda, Yoshitaka, Taniguchi, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918451/
https://www.ncbi.nlm.nih.gov/pubmed/1904419
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01861.x

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