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Exact association test for small size sequencing data

BACKGROUND: Recent statistical methods for next generation sequencing (NGS) data have been successfully applied to identifying rare genetic variants associated with certain diseases. However, most commonly used methods (e.g., burden tests and variance-component tests) rely on large sample sizes. Not...

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Detalles Bibliográficos
Autores principales:	Lee, Joowon, Lee, Seungyeoun, Jang, Jin-Young, Park, Taesung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918458/ https://www.ncbi.nlm.nih.gov/pubmed/29697368 http://dx.doi.org/10.1186/s12920-018-0344-z

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