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Population-based statistical inference for temporal sequence of somatic mutations in cancer genomes
BACKGROUND: It is well recognized that accumulation of somatic mutations in cancer genomes plays a role in carcinogenesis; however, the temporal sequence and evolutionary relationship of somatic mutations remain largely unknown. METHODS: In this study, we built a population-based statistical framewo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918460/ https://www.ncbi.nlm.nih.gov/pubmed/29697365 http://dx.doi.org/10.1186/s12920-018-0352-z |