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BCL11B Drives Human Mammary Stem Cell Self-Renewal In Vitro by Inhibiting Basal Differentiation
The epithelial compartment of the mammary gland contains basal and luminal cell lineages, as well as stem and progenitor cells that reside upstream in the differentiation hierarchy. Stem and progenitor cell differentiation is regulated to maintain adult tissue and mediate expansion during pregnancy...
Autores principales: | Miller, Daniel H., Jin, Dexter X., Sokol, Ethan S., Cabrera, Janel R., Superville, Daphne A., Gorelov, Rebecca A., Kuperwasser, Charlotte, Gupta, Piyush B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918530/ https://www.ncbi.nlm.nih.gov/pubmed/29503088 http://dx.doi.org/10.1016/j.stemcr.2018.01.036 |
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