Detection of Hepatitis C Virus Infection by Enzyme‐linked Immunosorbent Assay System Using Core Protein Expressed in Escherichia coli

Enzyme‐linked immunosorbent assay of the core protein of hepatitis C virus (HCV) expressed in E. coli led to detection of the antibody against this virus in patients with chronic hepatitis. Some of the negative results obtained using a different viral protein became positive with this E. coli‐expres...

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Detalles Bibliográficos
Autores principales: Muraiso, Kanae, Hijikata, Makoto, Kato, Nobuyuki, Shimotohno, Kunitada, Okazaki, Nobuo, Ohkoshi, Showgo, Uura, Masashi, Kaneko, Shuichi, Kobayashi, Kenichi, Omata, Masao, Ohnishi, Hiroo, Mutou, Yasutoshi, Hattori, Nobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918576/
https://www.ncbi.nlm.nih.gov/pubmed/1716622
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01914.x
Descripción
Sumario:Enzyme‐linked immunosorbent assay of the core protein of hepatitis C virus (HCV) expressed in E. coli led to detection of the antibody against this virus in patients with chronic hepatitis. Some of the negative results obtained using a different viral protein became positive with this E. coli‐expressed viral protein, and were also positive for the viral RNA. Thus, use of the core protein of HCV facilitates accurate detection of HCV infection.

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