Detection of Hepatitis C Virus Infection by Enzyme‐linked Immunosorbent Assay System Using Core Protein Expressed in Escherichia coli

Enzyme‐linked immunosorbent assay of the core protein of hepatitis C virus (HCV) expressed in E. coli led to detection of the antibody against this virus in patients with chronic hepatitis. Some of the negative results obtained using a different viral protein became positive with this E. coli‐expres...

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Autores principales: Muraiso, Kanae, Hijikata, Makoto, Kato, Nobuyuki, Shimotohno, Kunitada, Okazaki, Nobuo, Ohkoshi, Showgo, Uura, Masashi, Kaneko, Shuichi, Kobayashi, Kenichi, Omata, Masao, Ohnishi, Hiroo, Mutou, Yasutoshi, Hattori, Nobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918576/
https://www.ncbi.nlm.nih.gov/pubmed/1716622
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01914.x
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author Muraiso, Kanae
Hijikata, Makoto
Kato, Nobuyuki
Shimotohno, Kunitada
Okazaki, Nobuo
Ohkoshi, Showgo
Uura, Masashi
Kaneko, Shuichi
Kobayashi, Kenichi
Omata, Masao
Ohnishi, Hiroo
Mutou, Yasutoshi
Hattori, Nobu
author_facet Muraiso, Kanae
Hijikata, Makoto
Kato, Nobuyuki
Shimotohno, Kunitada
Okazaki, Nobuo
Ohkoshi, Showgo
Uura, Masashi
Kaneko, Shuichi
Kobayashi, Kenichi
Omata, Masao
Ohnishi, Hiroo
Mutou, Yasutoshi
Hattori, Nobu
author_sort Muraiso, Kanae
collection PubMed
description Enzyme‐linked immunosorbent assay of the core protein of hepatitis C virus (HCV) expressed in E. coli led to detection of the antibody against this virus in patients with chronic hepatitis. Some of the negative results obtained using a different viral protein became positive with this E. coli‐expressed viral protein, and were also positive for the viral RNA. Thus, use of the core protein of HCV facilitates accurate detection of HCV infection.
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spelling pubmed-59185762018-05-11 Detection of Hepatitis C Virus Infection by Enzyme‐linked Immunosorbent Assay System Using Core Protein Expressed in Escherichia coli Muraiso, Kanae Hijikata, Makoto Kato, Nobuyuki Shimotohno, Kunitada Okazaki, Nobuo Ohkoshi, Showgo Uura, Masashi Kaneko, Shuichi Kobayashi, Kenichi Omata, Masao Ohnishi, Hiroo Mutou, Yasutoshi Hattori, Nobu Jpn J Cancer Res Rapid Communication Enzyme‐linked immunosorbent assay of the core protein of hepatitis C virus (HCV) expressed in E. coli led to detection of the antibody against this virus in patients with chronic hepatitis. Some of the negative results obtained using a different viral protein became positive with this E. coli‐expressed viral protein, and were also positive for the viral RNA. Thus, use of the core protein of HCV facilitates accurate detection of HCV infection. Blackwell Publishing Ltd 1991-08 /pmc/articles/PMC5918576/ /pubmed/1716622 http://dx.doi.org/10.1111/j.1349-7006.1991.tb01914.x Text en
spellingShingle Rapid Communication
Muraiso, Kanae
Hijikata, Makoto
Kato, Nobuyuki
Shimotohno, Kunitada
Okazaki, Nobuo
Ohkoshi, Showgo
Uura, Masashi
Kaneko, Shuichi
Kobayashi, Kenichi
Omata, Masao
Ohnishi, Hiroo
Mutou, Yasutoshi
Hattori, Nobu
Detection of Hepatitis C Virus Infection by Enzyme‐linked Immunosorbent Assay System Using Core Protein Expressed in Escherichia coli
title Detection of Hepatitis C Virus Infection by Enzyme‐linked Immunosorbent Assay System Using Core Protein Expressed in Escherichia coli
title_full Detection of Hepatitis C Virus Infection by Enzyme‐linked Immunosorbent Assay System Using Core Protein Expressed in Escherichia coli
title_fullStr Detection of Hepatitis C Virus Infection by Enzyme‐linked Immunosorbent Assay System Using Core Protein Expressed in Escherichia coli
title_full_unstemmed Detection of Hepatitis C Virus Infection by Enzyme‐linked Immunosorbent Assay System Using Core Protein Expressed in Escherichia coli
title_short Detection of Hepatitis C Virus Infection by Enzyme‐linked Immunosorbent Assay System Using Core Protein Expressed in Escherichia coli
title_sort detection of hepatitis c virus infection by enzyme‐linked immunosorbent assay system using core protein expressed in escherichia coli
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918576/
https://www.ncbi.nlm.nih.gov/pubmed/1716622
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01914.x
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