Co‐production of Interleukin‐1 and Interleukin‐6 in Tumor Cell Lines Elaborating Colony‐stimulating Factors

Six carcinoma cell lines elaborating colony‐stimulating factors (CSFs) were examined by enzyme‐linked immtmosorbent assay and Northern blotting to determine whether or not they co‐produced interleukin‐lα (IL‐lα), IL‐lβ and IL‐6. All 6 cell lines were co‐producers; IL‐lα was produced in all 6, IL‐6 i...

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Detalles Bibliográficos
Autores principales: Okuno, Yoshiaki, Takahashi, Takayuki, Suzuki, Akira, Fukumoto, Manabu, Nakamura, Kishiko, Imura, Hiroo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918582/
https://www.ncbi.nlm.nih.gov/pubmed/1910025
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01917.x
Descripción
Sumario:Six carcinoma cell lines elaborating colony‐stimulating factors (CSFs) were examined by enzyme‐linked immtmosorbent assay and Northern blotting to determine whether or not they co‐produced interleukin‐lα (IL‐lα), IL‐lβ and IL‐6. All 6 cell lines were co‐producers; IL‐lα was produced in all 6, IL‐6 in 5 and IL‐1β in 3 of them. These results indicate that IL‐1 and IL‐6 are commonly co‐produced in CSF‐producing tumors.

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