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Ki‐ras Activation in Pancreatic Carcinomas of Syrian Hamsters Induced by N‐Nitrosobis(2‐hydroxypropyl)amine

Five pancreatic carcinomas induced by N‐nitrosobis(2‐hydroxypropyl)amine in Syrian golden hamsters were analyzed for activation of Ki‐ras at codons 12 and 13, using the polymerase chain reaction and direct sequencing. The Ki‐ras gene was shown to be activated in four of the five carcinomas, and the...

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Detalles Bibliográficos
Autores principales: Ushijima, Toshikazu, Tsutsumi, Masahiro, Sakai, Ryuichi, Ishizaka, Yukihito, Takaku, Fumimaro, Konishi, Yoichi, Takahashi, Michihito, Sugimura, Takashi, Nagao, Minako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918598/
https://www.ncbi.nlm.nih.gov/pubmed/1657847
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01928.x