Establishment of Immunodeficient Retinal Degeneration Model Mice and Functional Maturation of Human ESC-Derived Retinal Sheets after Transplantation

Increasing demand for clinical retinal degeneration therapies featuring human ESC/iPSC-derived retinal tissue and cells warrants proof-of-concept studies. Here, we established two mouse models of end-stage retinal degeneration with immunodeficiency, NOG-rd1-2J and NOG-rd10, and characterized disease...

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Detalles Bibliográficos
Autores principales: Iraha, Satoshi, Tu, Hung-Ya, Yamasaki, Suguru, Kagawa, Takahiro, Goto, Motohito, Takahashi, Riichi, Watanabe, Takehito, Sugita, Sunao, Yonemura, Shigenobu, Sunagawa, Genshiro A., Matsuyama, Take, Fujii, Momo, Kuwahara, Atsushi, Kishino, Akiyoshi, Koide, Naoshi, Eiraku, Mototsugu, Tanihara, Hidenobu, Takahashi, Masayo, Mandai, Michiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918611/
https://www.ncbi.nlm.nih.gov/pubmed/29503091
http://dx.doi.org/10.1016/j.stemcr.2018.01.032

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