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Anticellular and Antitumor Activity of Duocarmycins, Novel Antitumor Antibiotics

The anticellular and antitumor activities of novel antitumor antibiotics, duocarmycins (DUMs), were examined against human and murine tumor cells. DUMs consist of live compounds, A, B(1), B(2), C(1), and C(2), which possess a pharmacophore similar to that of CC‐1065, a previously isolated antibiotic...

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Detalles Bibliográficos
Autores principales:	Gomi, Katsushige, Kobayashi, Eiji, Miyoshi, Katsunori, Ashizawa, Tadashi, Okamoto, Akihiko, Ogawa, Tatsuhiro, Katsumata, Shigeo, Mihara, Akira, Okabe, Masami, Hirata, Tadashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1992
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918644/ https://www.ncbi.nlm.nih.gov/pubmed/1544867 http://dx.doi.org/10.1111/j.1349-7006.1992.tb02360.x

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