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Functional Beta Cell Mass from Device-Encapsulated hESC-Derived Pancreatic Endoderm Achieving Metabolic Control
Human stem cells represent a potential source for implants that replace the depleted functional beta cell mass (FBM) in diabetes patients. Human embryonic stem cell-derived pancreatic endoderm (hES-PE) can generate implants with glucose-responsive beta cells capable of reducing hyperglycemia in mice...
Autores principales: | Robert, Thomas, De Mesmaeker, Ines, Stangé, Geert M., Suenens, Krista G., Ling, Zhidong, Kroon, Evert J., Pipeleers, Daniel G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918665/ https://www.ncbi.nlm.nih.gov/pubmed/29503087 http://dx.doi.org/10.1016/j.stemcr.2018.01.040 |
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