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DT‐5461, a New Synthetic Lipid A Analogue, Inhibits Lung and Liver Metastasis of Tumor in Mice

We have investigated the antimetastatic effect of a new synthetic lipid A analogue, of low endo‐toxicity, DT‐5461, against two highly metastatic tumor cell lines, L5178Y‐ML25 T‐lymphoma and B16‐BL6 melanoma cells in mice. Four intermittent i.v. administrations of DT‐5461 at intervals of 4 days resul...

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Detalles Bibliográficos
Autores principales:	Sato, Katsuaki, Saiki, Ikuo, Yoo, Yung Choon, Igarashi, Yu, Kiso, Makoto, Hasegawa, Akira, Azuma, Ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1992
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918675/ https://www.ncbi.nlm.nih.gov/pubmed/1452460 http://dx.doi.org/10.1111/j.1349-7006.1992.tb02725.x

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