Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo

Human pluripotent stem cell (hPSC)-derived kidney organoids may facilitate disease modeling and the generation of tissue for renal replacement. Long-term application, however, will require transferability between hPSC lines and significant improvements in organ maturation. A key question is whether...

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Detalles Bibliográficos
Autores principales: van den Berg, Cathelijne W., Ritsma, Laila, Avramut, M. Cristina, Wiersma, Loes E., van den Berg, Bernard M., Leuning, Daniëlle G., Lievers, Ellen, Koning, Marije, Vanslambrouck, Jessica M., Koster, Abraham J., Howden, Sara E., Takasato, Minoru, Little, Melissa H., Rabelink, Ton J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918682/
https://www.ncbi.nlm.nih.gov/pubmed/29503086
http://dx.doi.org/10.1016/j.stemcr.2018.01.041

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