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Inactivation of the p53 Gene Is not Required for Tumorigenesis of Medullary Thyroid Carcinoma or Pheochromocytoma

A polymerase chain reaction (PCR)‐mediated RNase protection analysis was performed to detect subtle genetic alterations of p53 in medullary thyroid carcinoma (MTC) and pheochromocytoma. None of the 30 pheochromocytomas showed abnormal RNase protection patterns. Only one of 32 MTCs showed an abnormal...

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Detalles Bibliográficos
Autores principales: Yana, Ikuo, Nakamura, Tsutomu, Shin, Eisei, Karakawa, Katsu, Kurahashi, Hiroki, Kurita, Yoshihiro, Kobayashi, Tetsuro, Mori, Takesada, Nishisho, Isamu, Takai, Shin‐ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918706/
https://www.ncbi.nlm.nih.gov/pubmed/1483923
http://dx.doi.org/10.1111/j.1349-7006.1992.tb02730.x