Absence of Activating Mutations in the Transmembrane Domain of the c‐erbB‐2 Proto‐oncogene in Human Lung Cancer

The rat neu gene is known to be activated by a point mutation in its predicted transmembrane domain. Overexpression of the human homologue of neu, the c‐erbB‐2 gene, in human lung cancer has been reported, and a similar activating point mutation has been suggested. Therefore, we tested for possible...

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Detalles Bibliográficos
Autores principales: Sachse, Richard, Murakami, Yoshinori, Shiraishi, Masahiko, Hayashi, Kenshi, Sekiya, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918750/
https://www.ncbi.nlm.nih.gov/pubmed/1483946
http://dx.doi.org/10.1111/j.1349-7006.1992.tb02762.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918750/
https://www.ncbi.nlm.nih.gov/pubmed/1483946
http://dx.doi.org/10.1111/j.1349-7006.1992.tb02762.x

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