Cargando…
Absence of Activating Mutations in the Transmembrane Domain of the c‐erbB‐2 Proto‐oncogene in Human Lung Cancer
The rat neu gene is known to be activated by a point mutation in its predicted transmembrane domain. Overexpression of the human homologue of neu, the c‐erbB‐2 gene, in human lung cancer has been reported, and a similar activating point mutation has been suggested. Therefore, we tested for possible...
Autores principales: | Sachse, Richard, Murakami, Yoshinori, Shiraishi, Masahiko, Hayashi, Kenshi, Sekiya, Takao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1992
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918750/ https://www.ncbi.nlm.nih.gov/pubmed/1483946 http://dx.doi.org/10.1111/j.1349-7006.1992.tb02762.x |
Ejemplares similares
-
Amplification and overexpression of the EGF receptor and c-erbB-2 proto-oncogenes in human stomach cancer.
por: Lemoine, N. R., et al.
Publicado: (1991) -
Proto-oncogene c-erbB2 initiates rat primordial follicle growth via PKC and MAPK pathways
por: Li-Ping, Zheng, et al.
Publicado: (2010) -
Mutational Screening in Tyrosine-Kinase Domain of erbB1 And erbB2 Genes
por: ALONSO, Juan Manuel Fernández
Publicado: (2005) -
Expression of oncogenes in thyroid tumours: coexpression of c-erbB2/neu and c-erbB.
por: Aasland, R., et al.
Publicado: (1988) -
FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion
por: Benlimame, Naciba, et al.
Publicado: (2005)