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In vivo Antitumor Effects of Fluoropyrimidines on Colon Adenocarcinoma 38 and Enhancement by Leucovorin

Antitumor effect and active metabolites of fluoropyrimidines were examined in mice with transplant‐able colon adenocarcinoma 38 (Co 38). 5‐Fluoro‐2′‐deoxj uridine (FUdR) treatment resulted in a much higher level of free 5‐fluoro‐2′‐deoxyuridine‐5′‐monophosphate in the tumor than 5‐rluorouracil (5‐FU...

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Detalles Bibliográficos
Autores principales:	Iigo, Masaaki, Nishikata, Ken‐ichi, Hoshi, Akio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1992
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918824/ https://www.ncbi.nlm.nih.gov/pubmed/1387127 http://dx.doi.org/10.1111/j.1349-7006.1992.tb00120.x

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