Short Sequence in LI Region of Human Papillomaviruses Correlates with Clinical Pictures and Grouping by Cross‐hybridization

A consensus primer‐mediated polymerase chain reaction devised to amplify a short sequence in LI region (L1‐PCR) efficiently detected genital human papillomaviruses (HPVs) in clinical materials. Nucleotide sequencing of the amplified fragment showed that L1‐PCR is also applicable to hitherto unsequen...

Descripción completa

Detalles Bibliográficos
Autores principales: Iwamoto, Aikichi, Yoshikawa, Hiroyuki, Kitagawa, Kyoko, Igarashi, Hiroko, Kawana, Takashi, Yoshikura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918827/
https://www.ncbi.nlm.nih.gov/pubmed/1324233
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00107.x
Descripción
Sumario:A consensus primer‐mediated polymerase chain reaction devised to amplify a short sequence in LI region (L1‐PCR) efficiently detected genital human papillomaviruses (HPVs) in clinical materials. Nucleotide sequencing of the amplified fragment showed that L1‐PCR is also applicable to hitherto unsequenced HPVs. By comparing the amplified 210 nucleotides HPVs were classified into six groups, which are consistent with clinical pictures and a grouping based on cross‐hybridization under the stringent condition.

Ejemplares similares